ABSTRACT
Aim: This study was conducted to estimate and correlate salivary thiocyanate (SCN) levels in periodontally healthy subjects, smokers, nonsmokers, and gutka‑chewers with chronic periodontitis. Methodology: The study population consisted of 40 systemically healthy subjects in the age group of 18–55 years that was further divided into four groups: Control, smokers, nonsmokers, and gutka‑chewers with chronic periodontitis. Gingival index (GI) (Loe and Silness‑1963), probing depth (PD), clinical attachment loss was assessed. Estimation of SCN was performed by ultraviolet spectrophotometer at 447 nm wavelength. Statistical analysis was performed using the one‑way ANOVAs Welch test and Pearson’s correlation test using SPSS version 17 software. Results: Results showed statistically significant increase in SCN levels in smokers as compared to gutka‑chewers with chronic periodontitis, control, and nonsmokers with chronic periodontitis subjects. Significantly higher PD and loss of attachment were seen in smokers group compared with other groups. A negative correlation observed between the GI and thiocyanate levels. Conclusion: The present study revealed a significant increase in SCN levels in smokers with periodontitis as compared to nonsmokers.